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NEW ORLEANS & OSAKA, Japan--(BUSINESS WIRE)--Dec 9, 2013--Takeda Pharmaceutical Company Limited (TSE:4502) today announced final Phase 1 and preliminary Phase 2 results of a study combining oral investigational MLN9708 administered twice a week with lenalidomide and dexamethasone in patients with newly diagnosed multiple myeloma (MM). The investigators reported a combined complete response and very good partial response (CR+VGPR) rate of 76 percent (46/62) and a 94 percent overall response rate (ORR; 58/62 ≥ partial response). Stringent complete response (sCR) was reached in 75 percent of patients that attained CR. Overall, drug-related serious adverse events (SAEs) were reported in 28 percent of patients (18/64), and drug-related grade 3 adverse events (AEs) in 58 percent of patients (37/64). There were no drug-related grade 4 AEs. These data were presented today at the 55 th American Society of Hematology (ASH) annual meeting held December 7-10 in New Orleans, LA.
NEW ORLEANS--(BUSINESS WIRE)--Dec 9, 2013--Seattle Genetics, Inc. (Nasdaq: SGEN) and Takeda Pharmaceutical Company Limited (TSE:4502) today announced updated overall survival data from two ADCETRIS (brentuximab vedotin) pivotal Phase 2 clinical trials in relapsed/refractory Hodgkin lymphoma (R/R HL) and relapsed/refractory systemic anaplastic large cell lymphoma (R/R sALCL) were presented at the 55 th American Society of Hematology (ASH) Annual Meeting and Exposition taking place in New Orleans, LA, December 7-10, 2013. ADCETRIS is an antibody-drug conjugate (ADC) directed to CD30. Median overall survival (OS) of 40.5 months was reported in R/R HL, and was not yet reached in R/R sALCL.
Doctors are reporting a major advance against leukemia and other blood cancers.
It's almost time to say goodbye to Lauren Dorsett before she moves to California, but we couldn't let her leave without letting a few people say goodbye.
A new defense against prostate cancer, the most common cancer in men in the United States, may come from a seaweed found off the coast of Florida.
(NAPSI)—There’s hopeful news for the estimated 2.5 million American men who are currently living with prostate cancer.i Recent studies and analyses have demonstrated that men with advanced prostate cancer are now living longer than ever.ii,iii While this is encouraging, managing the disease over a longer period of time may create physical and emotional burdens for both patients and their caregivers.
NEW YORK, N.Y. (Ivanhoe Newswire) -- They’re called genetically modified organisms; some even call GMO’s “frankenfoods.” The U.S. is the largest producer of them. You may think you can avoid them, but in reality most of the foods on your supermarkets shelves contain at least one GMO. Are they safe? Should you take genetically modified foods off your menu? When it comes to the GMO debate, things are moving too fast for people to digest.
October is “Breast Cancer Awareness Month” and one thing every woman wants to know is how to decrease their risk.
Breast cancer is about 100-times less common in men than women, but, American Cancer Society researchers estimate 410-men will die of breast cancer this year.
LAKEWOOD RANCH, Fla. -- The annual Sarasota-Manatee Making Strides Against Breast Cancer noncompetitive 5K walk to raise money for research and treatment was today at the Sarasota Polo Club in Lakewood Ranch with proceeds benefiting the American Cancer Society.
Suncoast residents are contributing information over time that will impact the way we prevent, and treat cancer. A study of this magnitude only comes about every thirty years, and local hospitals are opening their doors.
September is prostate cancer awareness month.
Harvard researchers say mammograms before age fifty could dramatically cut deaths from breast cancer.
HOLMES BEACH, Fla. - Every now and then, our paths cross with someone who impacts our lives for the better. For people who know Nancy Ambrose, they're grateful their paths have crossed hers.
The risk of developing skin cancer can be lowered by taking simple precautions and knowing how to detect it at an early stage.
Numbers and letters may help provide an easier way to navigate information when choosing protection on the Suncoast.
Someone once said, build a better mouse-trap and the world will beat a path to your door. If the mouse is prostate cancer, we’ve been working on that trap for many years, making slow but significant progress.
SARASOTA - Sometimes when the big things in life knock you down, a little thing can come along and give you the courage to get back on your feet and fight again another day. And that’s the goal at just such a program at the American Cancer Society.
Leukemia is cancer of the blood forming tissue in the body, including bone marrow and the lymphatic system.
The American Cancer Society estimates 45,000 people will be diagnosed with it in 2013, and it will kill more than 38,000.
SARASOTA - New College and Ringling College of art and design battled it out on the football field.
SARASOTA - We are very excited about a new segment we are starting today: "The Amazing Women of the Suncoast." Our first amazing woman is Bambi Famous Kaine.
BRADENTON, Fla. - Do you ever wish when you see terrible things happening around you that you could do something to change them? That's the way a group of senior citizens felt in a Bradenton mobile home park. And wait until you hear what they accomplished.
CARACAS, Venezuela (AP) -- President Hugo Chavez, the fiery populist who declared a socialist revolution in Venezuela, crusaded against U.S. influence and championed a leftist revival across Latin America, died Tuesday at age 58 after a nearly two-year bout with cancer.