New research shows that among patients with mild to moderate Alzheimer disease (AD) a daily dosage of 2,000 IUs of vitamin E was effective in slowing functional decline and in reducing caregiver time in helping patients.
Researchers at the Minneapolis VA Health Care System examined 613 patients at 14 Veterans Affairs medical centers. Study participants received either 2,000 IU/day of vitamin E, 20 mg/d of memantine, a combination, or a placebo. Over the average follow-up time of 2.3 years, patients receiving vitamin E had slower functional decline than those receiving placebo. The annual rate of decline in activities of daily living reduced by 19 percent. Also, caregiver time was reduced by around 2 hours per day in the vitamin E group.