Question
Welcome!
|
||
Logout|My Dashboard

Key gene discovered in rare brain tumors

Print
Font Size:
Default font size
Larger font size

Posted: Tuesday, January 14, 2014 11:28 am | Updated: 11:32 am, Tue Jan 14, 2014.

Researchers have discovered a mutated gene that causes a type of tenacious, benign brain tumor that can have serious lifelong effects.

Researchers at Dana-Farber/Boston Children’s Cancer and Blood Disorders Center, Massachusetts General Hospital, and the Broad Institute of MIT and Harvard believe their discovery is encouraging because it may be possible to attack the tumors with targeted drugs already in use for other kinds of tumors. The mutated gene, called BRAF, was found in all samples of tumors called papillary craniopharyngiomas. The investigators were surprised to discover that the mutated BRAF gene was the sole driver of 95 percent of the papillary craniopharyngiomas they had analyzed, instead of multiple mutations.

“From a clinical perspective, identifying the BRAF mutation in the papillary tumors is really wonderful, because we have drugs that get into the brain and inhibit this pathway,” Sandro Santagata, MD, PhD, a co-senior author, was quoted as saying. "Previously, there were no medical treatments—only surgery and radiation—and now we may be able to go from this discovery right to a well-established drug therapy."

YOUR Health and Wellness News


Rules of Conduct

  • 1 Keep it Clean. Please avoid obscene, vulgar, lewd, racist or sexually-oriented language.
  • 2 Don't Threaten or Abuse. Threats of harming another person will not be tolerated. AND PLEASE TURN OFF CAPS LOCK.
  • 3 Be Truthful. Don't knowingly lie about anyone or anything.
  • 4 Be Nice. No racism, sexism or any sort of -ism that is degrading to another person.
  • 5 Be Proactive. Use the 'Report' link on each comment to let us know of abusive posts.
  • 6 Share with Us. We'd love to hear eyewitness accounts, the history behind an article.

Welcome to the discussion.

Featured Health Care Providers Sponsored directory

INTERVENTIONAL RADIOLOGIST

Gerald Grubbs, MD

View Profile >

CARDIOLOGY

James J. Fox, MD, F.A.C.C.

View Profile >

PROSTATE CANCER

Michael J. Dattoli, MD

View Profile >

GERIATRICS

Dr. Sarah Kagan, PhD, RN, FAAN

View Profile >

SPORTS MEDICINE

John T. Moor, MD

View Profile >

PRIMARY CARE

Jack E. Baron, MD

View Profile >

SUBMIT PHOTOS & VIDEOS | VIEW ALL PHOTOS & VIDEOS

Send your photos & videos to Pix@MySuncoast.com and you could be featured on ABC 7 & our website.